Sheikh Khasawneh has served Jordan in his capacity as a religious scholar and mufti in various roles. He is a former Mufti of the Jordanian Armed Forces, served as the Grand Mufti of Jordan between 2010-2017, and subsequently from 2019-2023. Khasawneh is also a member of the Jordanian Ifta Council and a member of the board of the World Islamic Sciences and Education University (WISE).