Professor Siddique is a neurologist and scientist known for his ground-breaking discoveries concerning genetic and molecular abnormalities. He was head of the team that discovered the cause behind the mysterious and deadly disorder known as amyotrophic lateral sclerosis (ALS). He studied at Dow Medical College in Karachi, where he earned his medical degree in 1973 before moving to the USA. He was a Professor of neurology and cell and molecular biology at Northwestern University’s Feinberg School of Medicine before becoming director of the university’s division of neuromuscular medicine.